Wednesday, December 5, 2012

Essay: In Lab Lit, Fiction Meets Science of the Real World

In Barbara Kingsolver?s new novel, ?Flight Behavior,? a central character is an entomologist tracking the effects of global climate change on monarch butterflies. The scientist, Ovid Byron, shows up at the Appalachian farm of Dellarobia Turnbow after she discovers a vast immigration of monarchs, displaced from their Mexican wintering spot by floods caused by global warming.

There?s a love story, of course, and a coming-of-age story (Dellarobia finally gets to go to college), and an intergenerational buddy story ? her precocious 6-year-old, Preston, bonds with Dr. Byron. But the take-away of this novel is that nature is off kilter, spinning out of control, changing before our very eyes.

As she did in ?Prodigal Summer? (2000), Ms. Kingsolver uses fiction to advocate for environmental awareness. But this advocacy is embedded in a compelling narrative of love and loss, opportunities taken or missed, characters who behave in complex and sometimes perplexing ways. Dellarobia Turnbow and her family are dirt-poor, and a summer of incessant rain has left them desperate. The timberland where she discovers the butterflies has already been promised to a lumber company. Save the butterflies or save the Turnbows?

Along with a suspenseful and sweetly told story, the science-nerd reader gets some basic ecology: ?The temperature at which a wet monarch will freeze to death,? Dr. Byron tells Dellarobia, ?is minus four degrees centigrade? (25 above zero Fahrenheit), meaning the monarchs are threatened by more than the proposed logging. That temperature range, Dr. Byron goes on, is ?an inevitable event, for this latitude.?

?Flight Behavior? fits neatly into a genre of serious fiction with a snappy new name: lab lit. I had never heard of it until I started browsing the Web for other novels about science; within minutes I came upon the webzine LabLit.com, which has ?Lab Lit Lists? for dozens of novels, films, plays and TV shows.

The Web site?s editor is Jennifer L. Rohn, a cell biologist at University College London and a novelist herself. The list is a work in progress, and anyone can contribute a title.

Lab lit is not science fiction, and in my opinion it?s not historical fiction about actual scientists (though some fictionalized biographies do appear on the list). Instead, in the Web site?s words, it ?depicts realistic scientists as central characters and portrays fairly realistic scientific practice or concepts, typically taking place in a realistic ? as opposed to speculative or future ? world.?

Popular writers like Carl Djerassi and Michael Crichton join Sinclair Lewis (?Arrowsmith?) as well as Richard Powers, whose brainy novels like ?The Gold Bug Variations? and ?Galatea. 2.2? have won many awards.

?Flight Behavior? is just one of several recent novels featuring scientists working on the big issues of our time. Ann Patchett?s ?State of Wonder? (2011) takes us into the jungles of the Amazon, where a researcher investigating a promising new fertility drug has gone missing.

The work of a field biologist ? one in the employ of a powerful pharmaceutical company ? is at the center of the story. The issues of exploitation of natural resources and people, of self-experimentation, of ignoring the incidental discovery of a potentially far more socially important but less lucrative drug, of the consequences of messing with nature combine to form the compelling crux of this book.

Ian McEwan?s ?Solar? (2010) gives us Michael Beard, a gluttonous, dishonest, womanizing Nobel-winning physicist, who is behind the development of a new form of photosynthesis that might reverse climate change ? and make him very rich. The problem is that the invention is not his ? though the inventor is no longer around to dispute the claim (and, in a neat twist, Beard was involved with, but not responsible for, his death).

One of my favorites on the Lab Lit List is Allegra Goodman?s ?Intuition? (2006), which deals with fraud in a biotech lab. Ms. Goodman did some of her research in a lab at the Whitehead Institute for Biomedical Research in Cambridge, and her portrayal of how questionable results can make it onto the record, despite the good intentions of the scientist involved, was eerily accurate.

?It completely nails this world,? Dr. Jerome Groopman, an oncologist and a professor of medicine at Harvard and the director of a laboratory there, said in a 2006 interview with The New York Times. ?It understands the psychology, the dynamics, the processes and pressures that exist in the current culture of science.?

?Mendel?s Dwarf? (1998), by Simon Mawer, an earlier example of lab lit, is about a geneticist, Benedict Lambert, who is not only a dwarf but distantly related to Gregor Mendel. The chapters alternate between Mendel?s little-recognized genius during his lifetime and Lambert?s search, using Mendelian principles, to find the gene for achondroplasia, or dwarfism. The book offers a palatable dose of elementary genetics interspersed with a compelling story, in which once again the scientist is something of an evil genius.

Katherine Bouton, a book reviewer for Science Times, is the author of ?Shouting Won?t Help: Why I ? and 50 Million Other Americans ? Can?t Hear You,? being published in February.

Source: http://www.nytimes.com/2012/12/04/science/in-lab-lit-fiction-meets-science-of-the-real-world.html?partner=rss&emc=rss

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